Higher voltage means needing thicker insulation, more grounding, more robust structure, more education for maintenance, more specialized tools to repair, and much higher expense on the battery cells.
"...thicker insulation..." True, but copper's a lot heavier than insulation. The weight savings in thinner wire more than makes up for higher levels of insulation required.
"...more grounding..." Uh, what? Proper grounding is proper grounding. A safety ground cable has to be adequate to carry full fault currents. Again, a lower-current, higher-voltage system needs less copper.
"...more robust structure..." Again, what? You can't have stuff shorting out no matter what the operating voltage.
"...more education for maintenance..." See above. "Stay clear of the high voltage" is the same at 200 volts as it is at 1000.
"...more specialized tools..." In all cases, special care needs to be taken to disco the high voltage. Once that's done, it's business as usual. And again, 200 volts or 1000 volts, you need to be very careful around it.
"...much higher expense on the battery cells." This one's just plain wrong. The 28S 4P battery cells (or whatever it is) in my SR could just as easily be arranged as 56S 2P, or 112S 1P, giving twice or four times the battery voltage, with no penalty for weight or volume in any case, except (again) less copper required for the higher-voltage systems.Those battery packs would be able to supply 1/2 or 1/4 of the current, but power delivered would be the same, as would capacity. It's a total wash.
The real technical differences are safety (I'm minimizing it, but of course higher voltages ARE at least somewhat more dangerous) and the heavier, higher gauge wiring required by lower-voltage systems. Of somewhat lesser importance is the ability to find drive devices (IGBTs, MOSFETs, whatever the engineer chooses to use) capable of operating at the design voltage and current levels, and a very real-world consideration is compatibility with current and future charging equipment.
To me, all of this adds up to basically "we need to do what the cars do", which at the moment means 300~400 VDC or so, maybe higher in the future. That compatibility issue I mentioned last may seem insignificant, but I suspect long-term, it's the most important consideration of all.