Here is a nice youtube video at the EEV blog about the 4680 cell. A guy who actually knows a little bit about electronics and is mildly impressed.
If the ideas behind the 4680 cell format are so obvious why has it taken a number of decades for anyone to implement them? Many innovations are obvious after the fact, physics is just physics. Brilliance is in seeing how to take best advantage of physics, and in the case of commercial products, costs also. The largest barrier to EV adoption is cost.
This guy is not considering the financial and manufacturing aspects of the 4680, which is the primary reason for the design. 5x energy implies 1/5 as many cells are required to make a battery pack of a given capacity, a great reduction in manufacturing and quality control operations and parts counts and thus, costs. There are also possible benefits in reliability. 6x power is significant because a battery pack of a given capacity will be capable of 20% more power, which also has implications for potential charge rates and charging times. The 16% range increase is a result of weight savings for a battery pack of a given capacity, so smaller battery pack can be used to achieve the same range goal, again reducing vehicle cost.
The primary commercial and practical significance of a battery cell design is the battery pack design it enables.