I have close to 40,000 miles on my 2015 and original Zero bearings and no noise or vibration at all and I have a heavy very loaded down bike all the time.
My 2012 bearings first failed at 18,000 miles with mostly the stock weight, and then about 15,000 miles after that when the bike was much heavier.
Because of the streamlining, my highway throttle usage was so little that the back tire would last about 20,000 miles. But the bearings would fail sooner than the tire. So I never had to get a new tire put on, I just got a new tire with a new wheel (and bearings) about 4 times over the next 2 years until the Vetter bike sort of retired in 2015.
So those with a 2014 or earlier bike, check the bearings frequently if you have 20,000 miles or more. Those with a 2015 or newer bike, I have yet to see one fail. Hoping for a 50,000 mile or more useful life out of the new generation wheels.
Not to say it isn't possible sooner than 50k, just it should be on par with the averages of other motorcycles. there is probably a bell curve where most average 50k miles, and some will go sooner and some will last longer. If anyone with a 2015 and up has had a bearing failure let us know so we know where the early part of the bell curve begins.