EVs in general, and the Zeros specifically, are designed to achieve a very high "efficiency" across a wide speed range. But the answer to the question I THINK you're really asking is, "as slowly as possible".
When I use the term "efficiency", I'm talking in the purely Physics sense; the ratio of the energy consumed over time to the amount of work done. "Work" done by a vehicle is dominated by three things: wind resistance, rolling resistance, and potential energy gain/loss by gaining/losing altitude. The first two always increase as speed increases; wind resistance in particular rises VERY fast as speed increases. Someone said in another thread that wind resistance rises proportional to the FOURTH power of vehicle speed.
So if you ride faster, your actual "efficiency" won't change much -- a few percent unless we're talking about extremely high or low speeds. The amount of energy expended/gained by climbing or losing elevation will rise directly proportional to your speed, as will rolling resistance, but since you'll finish the ride faster, the total amount of energy lost to those two things will be nearly a wash.
It's wind resistance that makes the big difference. Since it rises so fast as speed increases, and is dominant above very low speeds, the faster you ride, the more work has to be done to split the air, which isn't an efficiency loss per se (the bike IS doing more work), but it will reduce your range dramatically.
So the technical answer to the question you asked is, it doesn't make much difference in terms of actual EFFICIENCY except at very low or very high speeds. But the amount of energy it costs to make a trip will rise as your speed rises, at any reasonable road speed, so you'll always pay less, and have more range, if you ride as slowly as possible.