Unfortunately, it's really all math and formulas, but in a nutshell,
Mars motors make 72 rpms per volt, so 48 volts equals 3456 rpms while 72 volts equals 5184 rpms.
This means that the 72 volt system has a broader power range.
The 48 volt system will easily do 65 mph, but it wouldn't be nearly as efficient as the 72 volt system,
so make sure that you balance your system to make it as efficient as possible.
You need to do the math. Say you have a 20" diameter rear wheel, now multiply that by 3.14 (pi), then multiply that by 5184 (motor rpms), now divide by 63360 (inches per mile) then multiply by 60 (minutes per hour), this gets you 308.29 mph if the motor ran at 1:1 with the rear wheel, too fast!! You need to reduce your speed through gearing, if you have a popular 60 tooth rear sprocket and you want a top speed of around 65 mph you would need a 13 tooth motor sprocket which would get you a top speed of 66.73 mph. (60/13=4.62) (308.29/4.62=66.73)
Remember, the higher the top speed, the slower the acceleration, so make sure that you balance your system.