My experience may be helpful here.
I have two routes to work, one I used for a couple of years or so takes me along three fast roads before I hit the 50mph speed limits approaching London. It's the shortest route without going on back roads all the way and is approximately 24 miles. In April last year, I bought a Honda NC750 and a couple of days in, I thought I'd try an alternative route that takes me down the M1. It's further, at 28 miles, but you spend much more time at high speed, so the journey time is still around 50 minutes. The NC was much more fuel efficient than my previous bikes, so I felt happier about the longer route. I also found the new route bypassed some of the traffic going into London and was therefore more relaxing. There was simply less work to do.
As I'd found a better route, I stuck to it all summer. The NC750 could handle it, no problem. I kept up with the faster traffic and would cruise at 85-90mph. My conclusion after 6 months with the NC750 was that it isn't a bike for motorways though. There's the wind from the lack of fairing, which also makes it cooler and wetter. There's also the lack of power at high speeds which limits your maneuverability.
I had bought the NC750 DCT mostly because I couldn't afford to go electric and we didn't have a dealership in the UK. It's about as close as you can get to a Zero S.
I then decided that I didn't want to go into winter with the NC750 and the M1 route and chopped it in for a VFR 1200FD, also with the DCT box (automatic). It was perfect for the motorway, less so in town. It certainly made my M1 commute more fun as it literally ate motorway traffic for breakfast. You need tons of power to be able to accelerate quickly when you're already doing 70mph. Neither the NC750 or the Zero SR have that and they both top out a little over 100mph. The VFR just started to wake up at 100mph and would just keep accelerating hard up to... Well, I never found out. When there was a gap between the traffic I would pin it and be up at 130mph in no time. I always keep my relative speed low, for safety, so I'd drop back to 80-90mph to leisurely pass the next clump of traffic. I didn't upset anyone, there aren't any speed cameras, I kept an eye out for coppers and most of all, it was fun!
Then Streetbike became a dealership and I was able to get my hands on a DSP for a reasonable price.
I'm back to my old route because I enjoy riding the Zero at lower speeds. It's difficult to explain, but I just don't get that urge to blast down the road like I did on all my ICE bikes. I'm convinced the lack of engine noise is a big part of that. I still go 80mph on the short sections of my original route, but each high speed run only lasts a couple of minutes. Where as I enjoyed high speeds on the VFR, I enjoy lower speeds more on the Zero.
If you really like the idea of getting a Zero, like I did, then I strongly recommend getting a very good screen fitted to it. Otherwise, for your commute, you'd be better off on a touring machine. A VFR or ZZR if you want to make it fun.
There are plenty of cheap bikes out there with decent fairings, which makes it all the more irksome that Zero haven't come up with one yet.