Unless you REALLY have to get those extra few ounces out of the battery. Running them 20 / 80 will be so much better for them in the long haul.
I have close to 100 KW storage on my house, yes I know apples to oranges but they ARE batteries nonetheless. After a year or so of tinkering, I finally convinced myself that NO you really do NOT need to squeeze that extra kilowatt out of it, and in return you double the expected life expectancy of the battery at XX capacity remaining.
For those of us who may only put a few K a year on the bike, this genuinely is a non ssue, but for those who ride them like us hillbilly's ride our pickups, that can become significant.
Aaron